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For clinical studies, sufficient preclinical testing should be performed using standardized extracts before they can be subjected to clinical studies

This supports immune health and promotes skin health by reducing hyperpigmentation and age spots

Beneficiaries should remain aware of these parameters as they may impact their coverage

For example, senescent astrocytes show upregulated expression of IL-6, IL-8, IL-1, MMP3, MMP10, and TIMP2, while neuroprotective factors such as IL-10, NGF (nerve growth factor), and BDNF (brain-derived neurotrophic factor) are downregulated (Lye et al., 2019)

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it introduces an uncontrolled variable into any protocol relying on precise dosing calculations