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Cosmos Study December 16, 2025 Dual-Team Study Team A:Kersten Bartelt, RNNicholas Volker Team B:Tony Dunnigan, MDEric Barkley Key Findings Among patients with type 2 diabetes, GLP-1 use was associated with a 32% lower fracture risk for those with either osteopenia or osteoporosis

Bennett et al

[1] It functions as a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist

When dietary changes and lifestyle modifications plateau, GLP-1 medications present an evidence-based pharmacological option to extend long-term weight loss success without requiring revision procedures

39 parallel (68, 7080) and 2 cross-over (69) studies were included in this study