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Among the complexes, the MRP7-sertraline complex had the most negative free energy of binding value (43.17 kcal/mol), whereas the MRP1-fluoxetine complex had the least negative value (33.64 kcal/mol)

Moscat J, Diaz-Meco MT (2012) p62: a versatile multitasker takes on cancer

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Cagrilintide is a synthetic 39-amino acid acylated peptide analog classified as a dual amylin and calcitonin receptor agonist (DACRA), available as a lyophilized powder for laboratory research

Unlike benzodiazepines or other sedatives, it doesn't appear to create tolerance requiring escalating doses or produce withdrawal symptoms upon cessation