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Capsaicin induces a slow inward current which is not mediated by substance P in substantia gelatinosa neurons of the rat spinal cord

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Methylene blue is used to treat UTI symptoms as an antiseptic and mild analgesic in some oral medications, reducing discomfort and bacterial growth

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Chronic inflammatory cytokines like interleukin-6 and tumor necrosis factor-alpha can suppress ovarian steroidogenesis by decreasing enzyme activity necessary to produce estrogen and progesterone