We first probed for sAC expression by immunoblotting and detected abundant protein expression in mouse hearts and specific heart chambers (Figure 2A)
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Additionally, the infusion of native human GIP (142) into cardiac myocytes isolated from embryonic mouse hearts inhibited the increase in brain natriuretic peptide (BNP) and transforming growth factor- (TGF- 1) mRNA expression induced by angiotensin II (Ang II) [13]
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