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About 25% of adults in the US meet this criterion.[ref][ref] Other studies call levels from 150-999 mg/dl mild to moderate hypertriglyceridemia

TREM-2 is expressed in lipid-associated macrophages that drive pathologies such as atherosclerosis, obesity, metabolic dysfunction-associated steatotic liver disease, myocardial remodeling, and fibrosis 6971

J Neurosci 2002;22:10018-10029

Common (usually temporary) Nausea, fullness, decreased appetite Heartburn, burping, mild constipation or diarrhea Fatigue, headache, injection-site tenderness Less common Gallbladder issues (rare) Pancreatitis symptoms (severe abdominal painseek care) Allergic reaction (stop and contact provider) Who should avoid/ use caution Personal/family history of medullary thyroid carcinoma (MTC) MEN2 (Multiple Endocrine Neoplasia syndrome type 2) Active pancreatitis, severe GI disease, or pregnancy *This is educational and not medical advice

Diabetic retinopathy complications have been observed with rapid glycemic improvement, particularly with semaglutide

That means certain meals can hit the small intestine faster than before, especially foods that are high in sugar or eaten too quickly