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This process occurs through the direct binding of RSL3 to USP11, resulting in its inactivation and subsequent induction of ubiquitination and degradation of NRF2 protein in these cells [122]

Nat Rev Dis Primers 6(1):123 De Sanctis V, Soliman AT, Canatan D, Yassin MA, Daar S, Elsedfy H, Di Maio S, Raiola G, Corrons J-LV, Kattamis C (2019) Thyroid disorders in homozygous -thalassemia: current knowledge, emerging issues and open problems

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It is best to consult a doctor to determine the most suitable option for you based on your individual health needs and tolerability

Oxford, UK: Academic Press