can i start on a higher dose of semaglutide What was everyone's starting dose, and tapering up timeline and dose? : r/ Weight Loss Med Spa Georgia

Long-Term Considerations Weight Regain After Discontinuation Both medications are associated with weight regain after discontinuation: STEP 1 extension data showed that participants who stopped semaglutide regained approximately two-thirds of their lost weight over the following year (Wilding et al., Diabetes, Obesity and Metabolism , 2022) Long-term data for tesofensine is more limited, but weight regain is expected given that the appetite-suppressing mechanism ceases when the medication is stopped This underscores the importance of viewing these medications as long-term or indefinite treatments for chronic obesity management, rather than short-term interventions

The two of them then take turns answering a few of their favorite audience questions in a not-so rapid-fire style Q&A

doi: 10.1007/s00414-008-0262-2

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