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Other pathways proteins 17-HSD2 is a microsomal enzyme that catalyzes the oxidation of sex steroids testosterone and estradiol (E2) to less active ketones androstenedione and estrone (E1) 85,86

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This is perhaps a little surprising, since IGF-1 is a growth promoting substance hence we would expect that it could promote growth for every type of cancer

Nat Chem Biol 16:13511360 Santoro MM (2020) The antioxidant role of non-mitochondrial CoQ10: mystery solved