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The original GLP-1 receptor agonist was exenatide, which itself was a synthetic version of exendin-4

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GLP-1, which is an incretin hormone made mainly in the small bowel, binds to GLP-1 receptors, which are spread throughout the body, including in the intestine, pancreas and even the brain

Additional roles include repairing damaged DNA and protecting cells from stress

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This is a well-established physiological phenomenon that occurs regardless of the weight loss method employed