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10.3748/wjg.v23.i48.8465 18 FaghihiH.Mehdi RajaeiS.MehrazinH.GolabdarS.BrooksD

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Since GLP-1 is prone to degradation by dipeptidyl peptidase 4, GLP-1 receptor agonists (GLP-1RAs) have been developed to surmount this degradation challenge

We hence establish a crucial role of GIPR signalling in peripheral neurons in the regulation of glucose homeostasis, but not body weight, under conditions of diet-induced obesity

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