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doi:10.1172/JCI118475 39

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Chun YS, Mehran RJ, Tzeng CD, Kee BK, Dasari A, Sepesi B, Conrad C, Aloia TA, Kopetz S , Vauthey J

12 Additionally, DPP4 was found to be significantly expressed in osteoclasts, and its activity was inhibited by the anti-resorptive drug denosumab, suggesting that DPP4 produced by osteoclasts could play a crucial role in bone remodeling and energy metabolism