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The group has completed a phase three clinical trial, according to a trial database

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290,291,292 Accumulating macrophages release cytokines and chemokines, including IL-1, IL-6, chemokine ligand 2 (CCL2), and TNF-, intensifying the inflammatory environment and aggravating nerve damage

Figure 10 shows results from the study in elderly subjects (140)

Ascorbic acid derivative 2-o--d-glucopyranosyl-l-ascorbic acid from the fruit of lycium barbarum modulates microbiota in the small intestine and colon and exerts an immunomodulatory effect on cyclophosphamide-treated BALB/c mice

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