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doi: 10.3389/fimmu.2026.1845654 Received 02 April 2026 Revised 07 April 2026 Accepted 21 April 2026 Published 11 May 2026 Volume 17 - 2026 Edited by Venkata Ramireddy Narala, Yogi Vemana University, India Reviewed by Farrah Kheradmand, Baylor College of Medicine, United States Homayon Ghiasi, Cedars Sinai Medical Center, United States Updates Copyright 2026 Cain, Hurrell, Shen, Speliakos and Akbari

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Future research should examine the combined effects of multiple nutrients on male fertility and reproductive hormones

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This process not only benefits physical healthsuch as increasing muscle mass and enhancing recoverybut also plays a role in cognitive function and mood regulation

These different signaling pathways, which are associated with ER activation and ER inhibition, respectively, depend on cell context with the balance of receptor activation determining the overall response of the cell 78