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As D23 could potentially form hydrogen bond with the activator, the loss of activity observed in the mutant supported such a model

They use the same active peptide

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It should be noted that replacing saturated fat with refined carbohydrates and sugars has not been shown to reduce cardiovascular disease

Inform patients that if symptoms of hypersensitivity reaction occur, stop taking BYDUREON BCISE and seek medical advice promptly [see Warnings and Precautions (5.7)]