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Semaglutide ameliorates ovariectomy-induced osteoporosis and increases the expression of -catenin, leading to increased bone formation and halted receptor activator of nuclear factor kappa- ligand (RANKLs) activation

Berberine could help, thanks to its role in increasing glucagon-like peptide-1 (GLP-1), a natural gut hormone that supports glucose metabolism, insulin sensitivity, and appetite control

2012;7:e36569

This creates a paradox

However, for those with weaker skin barrier functions