Curcumin (50 mg/kg), quercetin (50 mg/kg) and a combination of both were orally administered for 14 days before carrageenan injection in rats and compared with the reference nonsteroidal anti-inflammatory drug, indomethacin (10 mg/kg)
Neuroscience 158 , 177188 (2009)
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Type 4 is associated with mild metabolic acidosis that results from a reduction in proximal tubular ammonium ion efflux (secretion) secondary to hypoaldosteronism