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For example, excessive amounts of Vitamin D can lead to Vitamin D toxicity

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The company was proposing AVT04 as a biosimilar to J&Js Stelara (ustekinumab), which binds to binds to two cytokines, IL-12 and IL-23, that are involved in inflammatory and immune responses

Abdel-Razik RK, Mosallam EM, Hamed NA (2022) Deterioration of cytochrome C content and mitochondrial dysfunction in brain of male rats after sub-chronic exposure to thiamethoxam and protective role of N-acetylcysteine