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Characterized by emotional disturbances, stress, guilt, and treatment avoidance, DD affected approximately 45% of patients worldwide-a prevalence underscoring its clinical significance [Reference Parsa, Aghamohammadi and Abazari57]

Neuroprotective activities of curcumin in Parkinson's disease: a review of the literature

Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome

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These findings collectively suggest that the increased threonine catabolism to propionyl-CoA does not lead to an overall increase in propionyl-CoA levels, primarily due to a substantial decrease in the contribution from microbiome-derived propionate and the increase of propionyl-CoA flux to glucose synthesis