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Patients prescribed GLP-1RAs displayed a significantly reduced hazard ratio for the diagnosis of intestinal obstruction compared with patients prescribed insulin at 1, 3, and 5 years

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You can learn more about that here: 12 biomarkers to monitor if you take a GLP-1 medication

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In humans, the SHMT enzyme exists in two isoforms, with the cSHMT gene encoding the cytosolic/nuclear enzyme (cSHMT) and the mSHMT gene encoding a mitochondrial SHMT enzyme