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doi: 10.20945/2359-3997000000368 76 ZoicoEFranceschettiGChirumboloSRossiAPMazzaliGRizzattiVet al

Initially, liraglutide should be given to patients at a dose of 0.6 mg once daily for 1 week to increase drug tolerability

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On the other hand, chronic kidney disease causes fast excretion of cobalamin through urine, resulting in low levels

Incorporated into a unique class of selenoproteins, this trace element supports both endocrine regulation and neuronal defense (104)

Clinical observations suggest that long-term use of LDL-apheresis in patients with severe HoFH contributes to regression and stabilisation of atherosclerotic plaques, improves cardiovascular prognosis, and reduces xanthomata of the skin and tendons [260]