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they are a byproduct of hormone production

thus, neutralization assays indicate a binding event is occurring, but it may not be detectable by the in vitro binding assay used herein (Supplementary Figure 22d,e)

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Secondly, unlike the Fc fragment of IgG antibodies, albumin does not engage effector molecules of the immune system, thereby minimizing the risk of potential adverse effects 1

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Given the tremendous costs of treating cardiovascular disease and continuing renal replacement therapy, the suspected total benefits obtained from therapy should not be overlooked