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We next attempted to rescue mitochondrial oxidative phosphorylation and glycolysis by co-supplementation with antioxidants, both cell-wide (2.5 mM GSH and 25 M Trolox) and mitochondrial-targeted [10 nM mitoquinol (MQ) and 1 nM SKQ1] (22, 23)

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tirzepatide formulations are pH 7.48.0), and combining them can cause precipitation or degrade one or both compounds

The link with lipid metabolism has been provided by employing a siRNA for OCTN2, which lowered carnitine uptake triggering an increased formation of lipid droplets and a decreased cell proliferation

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