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These numbers are higher than standard hydration guidelines because your body is actively working against you
In HEK293 cells expressing human GIP receptor or GLP-1 receptor, tirzepatide potently stimulated cAMP accumulation by both receptors, and the potency of tirzepatide was similar to that of native GIP and approximately 13-fold weaker than that of GLP-1 in these assays [88]
WARNING: you don't want to hit the SI nerve as that can cause some damage
The GLP-1-induced hyperpolarization is accompanied by an increase in membrane conductance suggesting the opening of potassium channels (Williams et al., 2018)
Bibcode:2021Natur.599..136W
It activates pathways involved in glucose uptake and insulin sensitivity
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