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Concurrently, modulating the gut microbiome through specific probiotic supplements (e.g., Lactobacillus and Bifidobacterium strains with high myrosinase activity) represents a promising strategy to standardize and enhance the conversion of glucoraphanin to bioactive SFN, particularly when dietary SFN is obtained from cooked vegetables where plant myrosinase is inactivated (100, 101)
Chan, The CNC basic leucine zipper factor, Nrf1, is essential for cell survival in response to oxidative stress-inducing agents