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By contrast, non-viral vectors, including liposomes and polymeric nanoparticles, provide improved biocompatibility and lower immunogenicity, although often at the expense of reduced transfection efficiency (111)

doi: 10.1038/nbt.3935 103 RabbaniB.TekinM.MahdiehN

It allows fluid and soluble molecule passage while blocking leukocyte infiltration and binding growth factors (73)

This can result in a depletion of amino acids and key nutrients (such as zinc, selenium, B12, and iron/ferritin) needed for thyroid support, as well as for the synthesis of non-essential amino acids

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