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Med Hypotheses (2019) 131:109308

Ferroptosis encompassed glutamic acid, glutamine, cysteine, glutathione, and arachidonic acid

P., Liras, S

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Excessive expression of TNF and NF-B increases the levels of muscle-specific E3 ligases (MuRF1 and atrogin-1), ultimately leading to proteolysis in respiratory and limb muscles, manifesting as difficulties in ventilator weaning and muscle weakness in patients (73,74)