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Verdict: Direct comparison difficult due to different trial designs, but retatrutide's advantage appears substantial even accounting for flexible vs fixed dosing

While rare, it can cause redness, swelling, itching, and tearing in the eyes

A comparison of the average daily cost at launch of different brands of semaglutide revealed that the daily cost of Wegovy was higher in the US compared to France and Germany

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Further, AUR with an annual risk of less than 1% is found to be uncommon, but requires urgent bladder catheterization

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