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The effective role of natural product berberine in modulating oxidative stress and inflammation related atherosclerosis: Novel insights into the gut-heart axis evidenced by genetic sequencing analysis

doi: 10.1053/j.gastro.2010.04.054 67 WooYCLeeCHFongCHYXuATsoAWKCheungBMYet al

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Prokesch, A

These studies underscore the paradoxical role of arginine metabolism and availability depending on the circumstances (e.g., immune cells infiltration and the type of arginine metabolizing enzymes expressed in these cells in the TME) and type of tumor, implying that arginine supplementation might be interesting for some, but not other tumors (Table 3)