Under different types of stimulation, tissue microenvironments, or stress exposure conditions, enhanced glutaminolysis does not necessarily lead to an anti-inflammatory phenotype
Each triplicate set of host-AG samples was quantile normalized against a triplicate set of samples from the same host expressing orf74 as it did not produce any phenotypes in the AG screen
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In this study, we sought to elucidate the role of melatonin in regulating ILC2 metabolism and effector function, in the context of allergic airways disease
Glycyrrhizin inhibits the metabolism of diosbulbin B (Yang et al., 2024), promotes bile acid efflux by increasing the expression of Nrf2/Farnesoid X Receptor- Bile Salt Export Pump (FXR-BSEP)/Multidrug Resistance-Associated Protein (MRP)2/P-glycoprotein/UDP-glucuronosyltransferase 1A1(UGT1A1), modulates gut microbiota, alleviates inflammation and oxidative stress, and improves diosbulbin B-induced liver injury (Wang et al., 2025)
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