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This is a reasonable hypothesis based on each peptides individual research, though direct clinical trials studying the combination in humans are limited
Surgery success rates are generally good for pain relief (70 to 90% improvement in leg pain symptoms), but come with risks: infection, nerve damage, disc reherniation (5 to 15% recurrence rate after microdiscectomy), and adjacent segment disease with fusion (20 to 30% develop problems within 10 years)
Front Chem 11:1144347
PMID 15565145
In cases of severe deficiency, a course of injections may be given over several weeks before transitioning to maintenance treatment
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