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Development of an ultra-performance liquid chromatography-electrospray ionization-Orbitrap mass spectrometry method for determination of xanthopurpurin in rat plasma and its application to pharmacokinetic study

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Depletion of GSH with the GCL inhibitor BSO leads to gliosis and neuroinflammation in the rat brain, with a particular increase in levels of TNF ( Oxidative stress involves the damage to mtDNA, lipids, and proteins in the cell which can lead to neuroinflammation

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