Also, patients should be warned about the danger of taking folic acid in place of Vitamin B12, because the former may prevent anemia but allow progression of subacute combined degeneration
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Thus, decreased plasma UA levels may reflect decreased ability of the body to prevent superoxide and peroxynitrite from acting on cellular components and damaging the cell ( FIGURE 3 On the other hand, at increased levels, UA is considered as a marker of oxidative stress ( In addition, an altered purine catabolism has also been demonstrated in subjects with cocaine addition ( Figure 3
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29 , 30 Moreover, Tribble et al reported more than ten-fold increase in the peak of free plasma cysteine after administering a single dose of 3g to participants taking a protein-restricted diet
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