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He added that GLP-1 therapies should form part of a structured, long-term treatment plan that includes dietary changes, lifestyle modifications and regular medical monitoring, rather than being viewed as short-term or cosmetic solutions

The SURPASS-CVOT trial, an ongoing cardiovascular outcomes study with approximately 12,500 participants, will provide more definitive long-term safety data regarding malignancy risk

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Thus, the consistent alteration of Bacteroides across these three conditions underscores its potential as a common gut microbial biomarker within the shared pathophysiology of metabolic-neuroendocrine dysfunction

& Sokolowski, C

Mechanisms of Ageing and Development, 125(2), 113-115