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In addition, artemisinin increases ROS levels, and FIN56 binds and activates squalene synthase to accumulate ROS ( P53, as a gene encoding transcription factor that controls the initiation of cell cycle, has dual regulatory effects on lipid peroxidation

Storage should follow standard protocols: store at -20C in lyophilized form protected from light and moisture

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suggested that ROS production increases due to NAD + reduction during aging and promotes hypoxia-inducible factor-1 (HIF-1) accumulation, leading to metabolic reprogramming, which is a hallmark of cancer

The analgesic effects of this plant are mediated by intricate interactions involving NO signaling, TRPV channel activation, and modulation of GABAergic pathways (Jabbari et al., 2025)