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Case 2 demonstrates a rapid improvement in mood with tirzepatide dose titration that preceded significant weight loss

P = .01), which is similar to findings from studies of GLP-1 use in the type 2 diabetes population, Do said

Unfortunately, few physicians are adequately trained in identifying and treating AWS

You can read more about this in our piece on the kindling effect

That is a reasonable practical consideration and a reasonable thing to raise with a prescriber

Stress and cortisol Chronic stress elevates cortisol, and high cortisol does more than make you feel on edge: It encourages fat storage, particularly around the abdomen where visceral fat accumulates