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But while they control appetite and help reduce body weight, they frequently trigger gastrointestinal side effects

Everyones experience is different, but for most people, this type of hair shedding is temporary rather than permanent

In the head-to-head SURMOUNT-5 trial (NEJM, 2025), tirzepatide produced 20.2% body weight loss vs 13.7% for semaglutide at 72 weeks, with similar side-effect profiles

However, under new guidance issued on 1 April 2026, it can now be prescribed on the NHS to patients with a BMI of 27 or greater who have already had a heart attack, stroke or serious circulation problem in their legs

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However, brand-name medications like Lexapro can come with a hefty price tag