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A disproportionality analysis model was performed to detect the potential signals of gastrointestinal AEs caused by GLP-1 RAs at both the class level and the drug generic name level ( Supplementary Table 2

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These are not typical reactions and must be evaluated by a medical professional right away

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Cardiomyopathy, cardiac arrhythmia, (likely due to the accumulation of long-chain fatty acids and acylcarnitines that cannot be oxidized), cardiac insufficiency and respiratory distress arise from CAC deficiency [120]

Retatrutide remains an investigational compound and is not approved for human use in any jurisdiction as of this writing