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The protocol consisted of using photodynamic therapy (PDT, via intense pulsed light at 400720 nm, administered in four sessions spaced two weeks apart), combined with a cream containing L-carnitine, licochalcone A, and decanediol, applied twice daily for 10 weeks

ICV = intracerebroventricular

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Particular caution is needed for patients with heart failure with reduced ejection fraction (HFrEF)

Glick, Z