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Concentrations of circulating homocysteine as well as its downstream products and key enzymes activities in the transsulfuration pathway were measured

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Spike protein inhibits CFTR recovery from endosomal recycling Under normal conditions, CFTR on the plasma membrane is subject to constitutive endosomal recycling in which misfolded or otherwise damaged CFTR is diverted towards destruction in the lysosome 47,48,49 (see Supplemental Fig