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SURMOUNT-5, the first head-to-head trial (published in NEJM, 2025), found tirzepatide produced about 20.2% average weight loss versus 13.7% for semaglutide over 72 weeks

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Qumicamente, es un pptido sinttico de 15 aminocidos derivado de una secuencia parcial identificada en el jugo gstrico humano

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The peptide also protects the gut lining, supports neurotransmitter function, and promotes the healing of both soft tissue and bone