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A study published in the journal Diabetes, Obesity and Metabolism found that patients on once-weekly semaglutide experienced significant decreases in serum B12 levels alongside reductions in zinc and albumin

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doi:10.1016/j.gene.2022.146663 Langan RC, Goodbred AJ

Gastrointestinal Disorders: Conditions like Crohn's disease, celiac disease, or a history of weight-loss surgery (like gastric bypass) can damage the exact parts of the intestine that are in charge of B12 absorption

Pantothenic Acid (Vitamin B5): Functions: It is involved in energy metabolism, helps maintain adrenal gland functions, and supports the processes involved in hormone production

Summary: B12 injections begin working at a cellular level immediately, though noticeable symptom improvement typically occurs within 4872 hours to several weeks depending on deficiency severity