They treat diabetes and metabolic risk factors
The resultant opening of voltage-dependent L-type Ca 2+ channels increases the intracellular concentration of Ca 2+ , which also acts as a second messenger, augmenting neurotransmitter release [33]
Most plant foods with colorful pigments are rich in polyphenols, so make sure your plate has lots of colorful foods on it

Retatrutide reconstitution chart Vial Size 5 mg BAC Water 1.0 mL Concentration 5 mg/mL (5,000 mcg/mL) 1 mg 0.20 mL (20 units) 2 mg 0.40 mL (40 units) 4 mg 0.80 mL (80 units) 6 mg Exceeds vial 9 mg Exceeds vial 12 mg Exceeds vial Vial Size 10 mg BAC Water 2.0 mL Concentration 5 mg/mL (5,000 mcg/mL) 1 mg 0.20 mL (20 units) 2 mg 0.40 mL (40 units) 4 mg 0.80 mL (80 units) 6 mg 1.20 mL - split draw or 2 vials 9 mg Requires 2 vials 12 mg Requires 2-3 vials Vial Size 20 mg BAC Water 2.0 mL Concentration 10 mg/mL (10,000 mcg/mL) 1 mg 0.10 mL (10 units) 2 mg 0.20 mL (20 units) 4 mg 0.40 mL (40 units) 6 mg 0.60 mL (60 units) 9 mg 0.90 mL (90 units) 12 mg 1.20 mL - split draw Vial Size 24 mg BAC Water 2.4 mL Concentration 10 mg/mL (10,000 mcg/mL) 1 mg 0.10 mL (10 units) 2 mg 0.20 mL (20 units) 4 mg 0.40 mL (40 units) 6 mg 0.60 mL (60 units) 9 mg 0.90 mL (90 units) 12 mg 1.20 mL - split draw Vial Size 30 mg BAC Water 3.0 mL Concentration 10 mg/mL (10,000 mcg/mL) 1 mg 0.10 mL (10 units) 2 mg 0.20 mL (20 units) 4 mg 0.40 mL (40 units) 6 mg 0.60 mL (60 units) 9 mg 0.90 mL (90 units) 12 mg 1.20 mL - split draw Units are U-100 insulin syringe units (1 mL = 100 units)

Journal of Clinical Endocrinology and Metabolism, 103 ,
GLP-1s are separately approved for type 2 diabetes and chronic kidney disease, which are not the focus of this advisory