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Furthermore, carnitine/acylcarnitine exert pleiotropic effects by interacting with the intracellular signal transduction network and participating in the regulation of a multitude of pivotal cellular physiological processes

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It was developed and FDA-approved in the 1990s (as Geref) to evaluate pituitary function in children with growth hormone deficiency, and it stayed on the market for years before the manufacturer withdrew it in 2009 for commercial reasons, not safety ones

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