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Lino, M

GST P1-1 inhibitors are typically non-productive analogues of glutathione which covers broad chemical space

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Glutathione, a powerful antioxidant, is included to help reduce visible signs of dullness and support the skin's natural radiance

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Consistently, GSTP-S184D also showed higher efficiency than GSTP (WT) in preventing LPS-induced HMGB1 export from the nucleus to cytoplasm in RAW264.7 cells, while GSTP-S184A almost had no effect on that (Figure 5B)