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doi: 10.1007/s00125-007-0890-y

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Conversely, CO-GHD patients tend to be less insulin-resistant than AO-GHD patients (84), and their IGF-I levels are generally lower than their AO-GHD counterparts due to relatively lower intra-portal insulin levels

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Importantly, post-exercise lactate concentrations were lower for the citrulline-supplemented group, which in turn, supports the mechanism of enhancing aerobic utilization during exercise