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It can be assumed that the intact, not damaged, neurons and glia would efficiently synthesize glutamate to substitute its deprivation due to an ischemic event and therefore compensate for the altered synthetic function of damaged neural cells

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This review focuses on the biosynthesis of EGT via microbial fermentation, explores its biosynthetic mechanisms, and summarizes the latest advancements for industrial EGT production using engineered microbial strains

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