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The primary outcome will be the percentage of participants with 3 step Early Treatment Diabetic Retinopathy Study (ETDRS) subject-level progression at five years, as well as secondary outcomes including 17 ocular and four systemic outcomes

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Mitochondrial dysfunction leads to the decrease of NAD + level, resulting in lysosomal acidification and impaired autophagy, and induces ferroptosis, involving the accumulation of iron in lysosomes and lipid peroxidation

Role of weight bias and patient-physician communication in the underutilization of bariatric surgery