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Other investigational compounds like acamprosate, neramexane, and AM-101 have also shown promise in clinical trials, though none are yet approved, highlighting the ongoing research need (Che et al., 2025)

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Clinical evidence indicates that bacterial DNA translocation is strongly associated with OHE, highlighting gut permeability as a critical determinant in the pathogenesis of HE [69]

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One of his requirements for clients on GLP-1s is that they have maintained a steady weight for more than six months