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For adults over 19, the recommended daily intake (RDI) is 2.4 micrograms (mcg)

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However, even at low levels, the alcohol can start affecting motor control, leading to slower reaction times and impaired judgement

Anyone taking methyl-donor-sensitive medications (some psychiatric drugs, methotrexate, methylated B-vitamin protocols at high doses): NNMT shares the methyl donor SAM, so theoretical interactions exist

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